Literature Review and Perspective:
Clinical Information Relating to Use of SureSkin® Hydrocolloid Dressings
Laura Bolton, Ph.D., Adjunct Associate Professor, Department of Surgery (Bioengineering)
University of Medicine and Dentistry of New Jersey
President, BoltonSCI, L. L. C.
A systematic literature review summarized and critically evaluated the evidence on safety and efficacy of using hydrocolloid dressings (HCD) in acute, chronic and self-managed (OTC) minor wound management and summarized available evidence on Euromed SureSkin
® II and SureSkin® Over The Counter (OTC) Hydrocolloid Dressings (SHD) within that context.
The highest level of evidence, at least two randomized controlled clinical trials or significant effects found in a meta-analysis or systematic review, supported the following effects of HCD compared to traditional gauze dressings: faster healing, better exudate management, improved patient comfort/reduced wound pain, skin and wound protection and cost effectiveness. One RCT supported improved scarring in HCDdressed post-operative closed incisions and one RCT each supported autolytic debridement of venous or pressure ulcers dressed with a HCD.
Preclinical studies established substantial equivalence of SHD to market leading HCD in composition and clinically relevant performance measures including biocompatibility, absorbance, microbial barrier properties and moisture-retention.
Healing, exudate management, patient comfort, debridement and infection outcomes of 1080 chronic and acute wounds experiencing up to 20 consecutive SHD dressing changes were similar to the best reported clinical outcomes for marketed HCD.
After reviewing the combined evidence, the author concluded that SHD are safe, effective options for meeting functional chronic and acute wound needs and are substantially equivalent to other HCD dressings currently indicated for use on wounds managed by professionals or by consumers using hydrocolloid OTC products.
A factorial, randomized trial of pentoxifylline or placebo, four-layer or single-layer compression, and knitted viscose or hydrocolloid dressings for venous ulcers.
Nelson EA, Prescott RJ, Harper DR, Gibson B, Brown D, Ruckley CV. School of Healthcare, University of Leeds, Leeds, UK. [email protected]